Duralast is a brand name for dapoxetine, a short-acting selective serotonin reuptake inhibitor (SSRI) specifically developed for the treatment of premature ejaculation (PE) in adult men. Unlike traditional antidepressants, dapoxetine has a rapid onset and short half-life, making it suitable for on-demand use rather than daily dosing. By increasing serotonin levels in synapses, Duralast enhances ejaculatory latency and improves control over ejaculation, leading to increased sexual satisfaction.
The usual starting dose of Duralast is 30 mg taken orally with a full glass of water one to three hours before anticipated sexual activity. Depending on response and tolerability, the dose may be increased to 60 mg, but no more than one dose should be used within a 24-hour period. Take the tablet with or without food, but avoid taking it with alcohol or recreational drugs to reduce the risk of dizziness or fainting. Duralast should only be taken as needed; it is not intended for continuous daily use.
Common side effects include nausea, headache, dizziness, dry mouth, diarrhea and insomnia. These effects are usually mild and transient. Dizziness and fainting can be minimized by rising slowly from sitting or lying positions and drinking adequate fluids. More serious adverse reactions such as mood changes, seizures or serotonin syndrome are rare but warrant immediate medical attention. Because Duralast can cause transient decreases in blood pressure and may interact with other medications, inform your doctor about all prescription and over-the-counter drugs you are taking, especially MAO inhibitors, other SSRIs, antidepressants, thioridazine, lithium and St. John’s wort. Combining dapoxetine with nitrates, recreational poppers or significant amounts of alcohol may cause dangerous hypotension.
Duralast is not recommended for men with significant liver or kidney impairment, heart failure, conduction abnormalities or a history of syncope. It is contraindicated in patients with bipolar disorder or other psychiatric illnesses. Use caution if you are also taking erectile dysfunction medications, as they may increase side effects. For those seeking rapid and reliable control of premature ejaculation, Duralast offers a clinically tested solution with a convenient on-demand dosing profile. Learn more about this treatment at Duralast.
The usual starting dose of Duralast is 30 mg taken orally with a full glass of water one to three hours before anticipated sexual activity. Depending on response and tolerability, the dose may be increased to 60 mg, but no more than one dose should be used within a 24-hour period. Take the tablet with or without food, but avoid taking it with alcohol or recreational drugs to reduce the risk of dizziness or fainting. Duralast should only be taken as needed; it is not intended for continuous daily use.
Common side effects include nausea, headache, dizziness, dry mouth, diarrhea and insomnia. These effects are usually mild and transient. Dizziness and fainting can be minimized by rising slowly from sitting or lying positions and drinking adequate fluids. More serious adverse reactions such as mood changes, seizures or serotonin syndrome are rare but warrant immediate medical attention. Because Duralast can cause transient decreases in blood pressure and may interact with other medications, inform your doctor about all prescription and over-the-counter drugs you are taking, especially MAO inhibitors, other SSRIs, antidepressants, thioridazine, lithium and St. John’s wort. Combining dapoxetine with nitrates, recreational poppers or significant amounts of alcohol may cause dangerous hypotension.
Duralast is not recommended for men with significant liver or kidney impairment, heart failure, conduction abnormalities or a history of syncope. It is contraindicated in patients with bipolar disorder or other psychiatric illnesses. Use caution if you are also taking erectile dysfunction medications, as they may increase side effects. For those seeking rapid and reliable control of premature ejaculation, Duralast offers a clinically tested solution with a convenient on-demand dosing profile. Learn more about this treatment at Duralast.
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