Azithromycin 500 mg won't provide immediate relief from UTI symptoms, but it works effectively behind the scenes to combat the bacterial infection. Here's a quick answer:

Noticeable Improvement: You might experience initial improvement within 24-48 hours of starting azithromycin.
Significant Relief: It typically takes 3-4 days to feel a significant difference in UTI symptoms.
Remember, these are estimates, and the timeframe can vary depending on individual factors.